Expresión de búsqueda: FLAP ENDONUCLEASES 
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Descriptor Inglés:   Flap Endonucleases 
Descriptor Español:   Endonucleasas de ADN Solapado 
Descriptor Portugués:   Endonucleases Flap 
Categoría:   D08.811.277.352.355.325.350
Definición Inglés:   Endonucleases that remove 5' DNA sequences from a DNA structure called a DNA flap. The DNA flap structure occurs in double-stranded DNA containing a single-stranded break where the 5' portion of the downstream strand is too long and overlaps the 3' end of the upstream strand. Flap endonucleases cleave the downstream strand of the overlap flap structure precisely after the first base-paired nucleotide, creating a ligatable nick. 
Nota Histórica Inglés:   2004; use FLAP ENDONUCLEASES (NM) 1994-2003; for FEN1 PROTEIN use EXODEOXYRIBONUCLEASE V 1997-2003; for RTH-1 NUCLEASE use EXODEOXYRIBONUCLEASE V 1996-2003 
Calificadores Permitidos Inglés:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Número del Registro:   38146 
Identificador Único:   D045585 

Ocurrencia en la BVS:
 

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